2000
Investigation on statistical Design of Experiment techniques
for reactor modeling and determination of reaction kinetics. Special attention has been paid to the various steps in the determination of the kinetic models. Starting from scratch linear screening designs separating main effects from secondary influences are discussed. Knowing the dominant effects, designs for determining the shape (linear effects, higher order terms and possible interactions) are mentioned. A survey was made of genuinely nonlinear designs for model discrimination and parameter accuracy refinement.