2002
This work is concerned with methods and routines for discrimination among rival kinetic models and for precise parameter estimation by means of Sequential Experimental Design (SED). The two main objectives of the work, defined as subtasks, are Subtask 1: To explain the different methods for SED by means of practical cases. Application of the methodology for single and complex reactions as well as for dynamic experiments will be treated in the present document. Subtask 2: To describe and compare software codes for SED developed by academic research groups as well as software vendor companies. This subtask is treated a separate
document entitled as “SED_codes”. The results of this work could be used to enhance the developments of commercial software concerning sequential design of experiments.
